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Rb(Phospho Ser608) Polyclonal Antibody, 100ul Protein Analysis subunit:Interacts with guanylate kinase-like domain

SKU: 1787344034

4.6
PLN123.75 PLN149.75

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Rb(Phospho Ser608) Polyclonal Antibody, 100ul Protein Analysis subunit:Interacts with guanylate kinase-like domainThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

subunit:Interacts with guanylate kinase-like domain of DLG1

This convenient kit allows for efficient and accurate detection of IL-6 in just one step

Mutations in this gene may be associated with iron overload in human patients

The acidic C-terminal region of the encoded protein can act as a transactivation domain

Alternative splicing results in several transcript variants encoding different isoforms

Rb(Phospho Ser608) Polyclonal Antibody, 100ul Protein Analysis subunit:Interacts with guanylate kinase-like domainThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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