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10.1056/NEJMoa1404037 22 PatelS

Factors Influencing Duration in the Body Dosage: Higher doses may remain in circulation slightly longer, though the difference can be marginal

The second class is inhibitors of the GLP-1 degrading enzyme, dipeptidyl pepitidase IV (Sitagliptin and related drugs) which can be given orally and increase the plasma level of GLP-1 and other peptides degraded by DPP-4

In addition to treating diabetes, these medications have been clinically proven to help with weight loss [3], making them a popular choice for individuals looking to shed pounds and improve their health markers