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Plant GPXLs, containing cysteine in their active site domain, may have dual roles, acting as glutathione peroxidase and thioredoxin peroxidase functions ( 2 O 2 and organic hydroperoxides, as well as their involvement in regulating cellular redox homeostasis by maintaining thiol/disulfide or NADPH/NADP+ ratios ( Deficiency in the activity of either GSH1 or GSH2 impairs GSH production, negatively impacting plant growth and development

(iii) If CMS receives a TIN-level data submission in the quality ASM performance category in accordance with paragraph (a)(1)(i) of this section for an ASM participant in a small practice, CMS scores the TIN-level submission and assigns that score to all individual ASM participants in the small practice, regardless of any TIN/NPI-level submission(s) received for one or more of those ASM participants

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