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McCann MR, Tamplin OJ, Rossant J, Seguin CA: Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development

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Interestingly, concomitant increases in metabolites related to methylated and oxidized waste products of nicotinamide were also observed in PBMCs, especially MeNAM, N -methyl-2-pyridone-5-carboxamide (Me2PY), and N -methyl-4-pyridone-5-carboxamide (Me4PY) [76] (Table 2)