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$AM966 Size:Solid 10 mg Smiles: [O-][N+](=O)C1C=CC(/C=C2\CNC/C(=C\C3C=CC(=CC=3)[N+]([O-])=O)/C\2=O)=CC=1$

AM966 Size:Solid 10 mg Smiles: [O-][N+](=O)C1C=CC(/C=C2\CNC/C(=C\C3C=CC(=CC=3)[N+]([O-])=O)/C\2=O)=CC=1

Name: AM966 Size:Solid 10 mg Smiles: [O-][N+](=O)C1C=CC(/C=C2\CNC/C(=C\C3C=CC(=CC=3)[N+]([O-])=O)/C\2=O)=CC=1
Brand: skorenge.com
SKU: 90089054502
Price: 115.00 USD
Availability: InStock
Rating: 4.1971 (18 reviews)

SKU: 90089054502

4.2

USD115.00 USD162.00

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Ships within 48 hours · Estimated delivery Aug 3 - Aug 8

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AM966 Size:Solid 10 mg Smiles: [O-][N+](=O)C1C=CC(/C=C2\CNC/C(=C\C3C=CC(=CC=3)[N+]([O-])=O)/C\2=O)=CC=1AM966 is a potent, selective, and orally active LPA(1) receptor antagonist which inhibits lung fibrosis in the mouse bleomycin model. In vitro, AM966 inhibited LPA stimulated intracellular calcium release from Chinese hamster ovary cells stably expressing human LPA(1) receptors and inhibited LPA induced chemotaxis of human IMR 90 lung fibroblasts expressing LPA(1) receptors. AM966 reduced lung injury, vascular leakage, inflammation and fibrosis at

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Description

Smiles: [O-][N+](=O)C1C=CC(/C=C2\CNC/C(=C\C3C=CC(=CC=3)[N+]([O-])=O)/C\2=O)=CC=1

Molecular Weight: 967

InChi: InChI=1S/2C7H10O7

21)14-5-2-4-12-9-18-10-13(16)15(12)14

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