AZD2858 46040 Smiles: CC1=C(CC(O)=O)C2=CC=CN=C2N1CC1=CC=C(C=C1C(F)(F)F)S(C)(=O)=O

Smiles: CC1=C(CC(O)=O)C2=CC=CN=C2N1CC1=CC=C(C=C1C(F)(F)F)S(C)(=O)=O

O'Connor MJ

This drug also prevents histamine-induced pain and itching of mucous membranes

which is comparable with the response seen with activated wt mALK

Mol Carcinog

AZD2858 46040 Smiles: CC1=C(CC(O)=O)C2=CC=CN=C2N1CC1=CC=C(C=C1C(F)(F)F)S(C)(=O)=OAZD2858 is a potent and GSK 3 inhibitor with an IC50 of 68 nM. AZD 2858 inhibits tau phosphorylation at the S396 site, and it activates Wnt signaling pathway. AZD2858 has a substantial impact on fracture healing. The fractures healed with a bony callus without an obvious endochondral component, suggesting that AZD2858 drives mesenchymal cells into the osteoblastic pathway. Product information CAS Number: 486424 20 8 Molecular Weight: 453. 52 Formula: