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The latest TEXAIS results in 2023 were negative with a certain trend, which might be limited by the small sample size, short treatment duration and lack of medium to long-term therapeutic evaluation

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Patients with liver disease, malnutrition, or those who consume 3 or more alcoholic drinks every day should use lower doses (2,000 mg daily) or avoid acetaminophen unless directed by their healthcare provider

Novo is not alone in investing in combination approaches: in AstraZenecas 2023 announcement of its acquisition of Eccogenes GLP-1 program, the manufacturer noted that they intend to combine the GLP-1 asset with other products in their portfolio (e.g., Farxiga, baxdrostat) in an effort to address obesity comorbidities (e.g., heart disease, kidney disease, metabolic syndrome)

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