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Conclusions The study findings indicate that the use of GLP-1 receptor agonists is not associated with an increased risk of self-harm, suicidal ideation, and suicide as compared to DPP-4 and SGLT-2 inhibitors among T2D patients

Some of the most common are hypothyroidism, a distal vacuolar myopathy, pancreatic exocrine and endocrine insufficiency, male hypogonadism, and idiopathic intracranial hypertension

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Here, Ekihiro Seki & team implicate the fungal sensing adaptor protein CARD9 in maintaining gut barrier integrity under metabolic stress, finding that the loss of fungal sensing exacerbates liver injury in a murine model of MASLD

JNK, c-Jun N-terminal kinases