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N4BP1 Polyclonal Antibody, 100ul Stepper A low level detected in

SKU: 4241470823

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N4BP1 Polyclonal Antibody, 100ul Stepper A low level detected inN4BP1 is a Protein Coding gene. NEDD4 Binding Protein 1 is a inhibitor of the E3 ubiquitin protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCHs substrates and impairing ubiquitination of substrates. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is ZC3H12C.

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Description

A low level detected in the spleen and lymph node

Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary

Also associates with MAPK14/p38-alpha

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily

A variant in this gene was associated with osteoarthritis

N4BP1 Polyclonal Antibody, 100ul Stepper A low level detected inN4BP1 is a Protein Coding gene. NEDD4 Binding Protein 1 is a inhibitor of the E3 ubiquitin protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCHs substrates and impairing ubiquitination of substrates. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is ZC3H12C.

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