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189 SmithS

The dimer interface is formed by the interaction between loop 2 of one monomer and loop 1 of the other, stabilized by hydrogen bonds and salt bridges, resulting in a more open and flexible active site pocket compared to other GCTs

doi: 10.1007/BF03349040 106 CohenMHarringtonJNarangIHamiltonJ

Dose Escalation Timeline After the initial four weeks at 2mg, the dosing increases in a structured pattern: Each increase happens after four weeks, assuming youre tolerating the current dose well

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