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Step 1: Consult your GP first Your first step should be a conversation with your NHS GP or prescribing clinician to rule out other causes for your symptoms and ensure your thyroid medication (like levothyroxine) dose is appropriate

Availability of data and materials The data used to support the findings of this study are available from the corresponding author upon request

Exercise also ramps up glutathione levels , with the attendant benefits to the immune system

299 Soluble urate may further exacerbate vascular inflammation and oxidative stress by promoting LDL oxidation, lipid peroxidation, and elevating hs-CRP levels