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NIBR3049 - CAS# 1260181-14-3 60002 Hochberg MC

NIBR3049 - CAS# 1260181-14-3 60002 Hochberg MC

Name: NIBR3049 - CAS# 1260181-14-3 60002 Hochberg MC
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NIBR3049 - CAS# 1260181-14-3 60002 Hochberg MCNIBR3049, CAS No. 1260181 14 3, also known as TCS 21311, is a potent and selective JAK3 inhibitor IC50 values of 8 nM. Product information CAS Number: 1260181 14 3 Molecular Weight: 526. 51 Formula: C27H25F3N4O4 Synonym: TCS 21311 Chemical Name: 3 [5 [4 (2 Hydroxy 2 methyl 1 oxopropyl) 1 piperazinyl] 2 (trifluoromethyl)phenyl] 4 (1H indol 3 yl) 1H pyrrole 2,5 dione Smiles: CC(C)(O)C(=O)N1CCN(CC1)C1=CC(C2=C(C3=CNC4=CC=CC=C43)C(=O)NC2=O)=C(C=C1)C(F)(F)F

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Description

Hochberg MC

Granstrom DE

It inhibits the activity of two 19S regulatory-particle-associated deubiquitinases

2013 Dec 20:jc20131688

22(17):3559-67

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