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[6] As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB: 1GLV, PDB: 1GSA, PDB: 1GSH, PDB: 1M0T, PDB: 1M0W, PDB: 2GLT, and PDB: 2HGS

Because of significant morbidity and mortality, multiple interventions are usually necessary to treat this condition

Glutaminase converts glutamine (predominantly derived from the liver but also from many other tissues) to glutamate and NH 4 + , with the NH 4 + being excreted in the urine