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The prevalence is estimated to be 1/14,300 (orpha.net/consor/cgi-bin/OC_Exp.php?Lng=EN&Expert=1332)

A metabolic signature of mitochondrial dysfunction revealed through a monogenic form of Leigh syndrome

In research settings, Tesamorelin is studied as a tool compound for investigating the GH/IGF-1 axis and its downstream effects on lipid metabolism, particularly in models relevant to visceral adipose tissue regulation