AT7519 Catalog No.:M10966-10 CUN25391 has CAS#105925-39-1
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AT7519 Catalog No.:M10966-10 CUN25391 has CAS#105925-39-1AT 7519 free base is a drug that acts as a multi cyclin dependent kinase inhibitor for Cdk1 cyclin B, Cdk2 Cyclin A, Cdk3 Cyclin E, Cdk4 Cyclin D1, Cdk5 p35, and Cdk6 Cyclin D3. AT7519 is an ATP competitive Cdk inhibitor but is inactive against all non Cdk kinases with the exception of GSK3. AT7519 shows potent antiproliferative activity in a variety of human tumor cell lines such as SW620. AT7519 induces activation of GSK 3 by down regulating GSK 3
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