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Fluvastatin D6 Sodium Catalog No.:M8292-10 When conjugated to chlorambucil

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Fluvastatin D6 Sodium Catalog No.:M8292-10 When conjugated to chlorambucilFluvastatin D6 sodium (XU 62 320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG CoA reductase inhibitor with an IC50 of 8 nM. Product information CAS Number: 2070009 35 5 Molecular Weight: 439. 48 Formula: C24H25FNNaO4 Chemical Name: sodium (3R, 5S, 6E) 7 [3 (4 fluorophenyl) 1 [(1, 1, 1, 3, 3, 3 H)propan 2 yl] 1H indol 2 yl] 3, 5 dihydroxyhept 6 enoate Smiles:

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Description

When conjugated to chlorambucil

Stephenson J

InChi: InChI=1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-5-13(24)16-14(6-11)29-8-12(17(16)25)9-1-3-10(23)4-2-9/h1-6

is discovered to inhibit JNK kinase by broad-base kinase selectivity profiling of a library of acrylamide kinase inhibitors based on the structure of imatinib using the KinomeSca approach

R112 does not inhibit phosphorylation of the Lyn target Syk (Y352)

Fluvastatin D6 Sodium Catalog No.:M8292-10 When conjugated to chlorambucilFluvastatin D6 sodium (XU 62 320 D6) is deuterium labeled Fluvastatin sodium. Fluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG CoA reductase inhibitor with an IC50 of 8 nM. Product information CAS Number: 2070009 35 5 Molecular Weight: 439. 48 Formula: C24H25FNNaO4 Chemical Name: sodium (3R, 5S, 6E) 7 [3 (4 fluorophenyl) 1 [(1, 1, 1, 3, 3, 3 H)propan 2 yl] 1H indol 2 yl] 3, 5 dihydroxyhept 6 enoate Smiles:

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