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Mechanism 1: caloric deficit and metabolic stress When you eat significantly fewer calories than your body requires, it enters a resource-allocation mode

The ideal scenario is that theres a conversation between the patient, the provider whos prescribing this medication, and at least one of the professionals working with the individual on their eating disorder, says Smith

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It can be conceived that absorption-modifying excipients (AMEs) that do not affect in vitro dissolution testing can be considered critical (i.e., concerning) for biowaivers since their effect on GI absorption (e.g., transit, intestinal permeability) would be overlooked

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