K-Ras G12C-IN-3 Catalog No.:M8513-10 Formula: C31H32N4O3

Formula: C31H32N4O3

a tyrosine kinase inhibitor

Probe ML188 is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action

InChi: InChI=1S/C77H96ClF3N10O10S4/c1-51(53-18-20-55(21-19-53)70-52(2)82-50-103-70)83-73(96)66-44-61(92)48-91(66)74(97)71(75(3

Nutlin-3 can block the MDMX–p53 interaction and induce the p53 pathway in retinoblastoma cells (Weri1) with IC50 of 0

K-Ras G12C-IN-3 Catalog No.:M8513-10 Formula: C31H32N4O3K Ras G12C IN 3 is a novel and irreversible inhibitor of mutant K ras G12C. IC50 value: Target: K ras G12C inhibitorFor more information, please see the following patent. Heterocyclic compounds as covalent inhibitors of G12C mutant K Ras protein useful for treating cancers, and preparation thereofBy Ren, Pingda; Liu, Yi; Li, Liansheng; Feng, Jun; Wu, Tao From PCT Int. Appl. (2014), WO 2014152588 A1 20140925. Product information CAS Number: 1629268 19