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Rb Polyclonal Antibody, 50ul[BT-AP07688] Custom RNA Oligos and the activation of transcription

SKU: 26280909082

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Rb Polyclonal Antibody, 50ul[BT-AP07688] Custom RNA Oligos and the activation of transcriptionThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and the activation of transcription factors

prostaglandin-endoperoxide synthase 1 has been identified as a moonlighting protein

and deletions at this locus are also associated with a decrease in aminoacylase activity

Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins

Interacts with NFKB1/p50

Rb Polyclonal Antibody, 50ul[BT-AP07688] Custom RNA Oligos and the activation of transcriptionThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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