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IL-2R Gamma Polyclonal Antibody, 50ul[BT-AP04492] Low retention tips Gene silencing studies with small

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IL-2R Gamma Polyclonal Antibody, 50ul[BT-AP04492] Low retention tips Gene silencing studies with smallCytokine receptor common subunit gamma encoded by IL2RG is an important signaling component of many interleukin receptors, including those of interleukin 2, 4, 7 and 21, and is thus referred to as the common gamma chain. Mutations in this gene cause X linked severe combined immunodeficiency (XSCID), as well as X linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

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Description

Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis

The protein recognizes mannose and N-acetylglucosamine on many microorganisms

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I

Mutations in this gene are a cause of Native American myopathy

This binding uncouples the receptor from the heterotrimeric G protein

IL-2R Gamma Polyclonal Antibody, 50ul[BT-AP04492] Low retention tips Gene silencing studies with smallCytokine receptor common subunit gamma encoded by IL2RG is an important signaling component of many interleukin receptors, including those of interleukin 2, 4, 7 and 21, and is thus referred to as the common gamma chain. Mutations in this gene cause X linked severe combined immunodeficiency (XSCID), as well as X linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

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