JNK-IN-7 - CAS# 1408064-71-0 Size:Solid 2 mg CN(C)C/C=C/C(=O)NC1C=CC(=CC=1)C(=O)NC1=CC(=CC=C1)NC1=NC(=C(Cl)C=N1)C1=CNC2=CC=CC=C21

CN(C)C/C=C/C(=O)NC1C=CC(=CC=1)C(=O)NC1=CC(=CC=C1)NC1=NC(=C(Cl)C=N1)C1=CNC2=CC=CC=C21

restores the deficient cytosolic translocation of HMGB1 and autophagy in cells overexpressing SNCA

Molecular Weight: 214

nhibits acute myelogenous leukemia cell growth in vitro and in vivo

2-10 hours) activates the MKK4-JNK-H2AX Pathway by inducing MKK4

JNK-IN-7 - CAS# 1408064-71-0 Size:Solid 2 mg CN(C)C/C=C/C(=O)NC1C=CC(=CC=1)C(=O)NC1=CC(=CC=C1)NC1=NC(=C(Cl)C=N1)C1=CNC2=CC=CC=C21JNK IN 7 is a relatively selective JNKs inhibitor(IC50= 1. 54 1. 99 0. 75 for JNK1 2 3); also bound to IRAK1, PIK3C3, PIP5K3 and PIP4K2C. Product information CAS Number: 1408064 71 0 Molecular Weight: 493. 56 Formula: C28H27N7O2 Synonym: JNK inhibitor Chemical Name: 3 [(2E) 4 (dimethylamino)but 2 enamido] N (4 {[4 (pyridin 3 yl)pyrimidin 2 yl]amino}phenyl)benzamide Smiles: CN(C)C C=C C(=O)NC1=CC(=CC=C1)C(=O)NC1C=CC(=CC=1)NC1=NC(=CC=N1)C1=CN=CC=C1