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CD6 Polyclonal Antibody, 100ul[BT-AP01767] Vacuum Filter providing a possible therapeutic target

SKU: 98320322293

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EUR141.00 EUR163.00

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CD6 Polyclonal Antibody, 100ul[BT-AP01767] Vacuum Filter providing a possible therapeutic targetIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. Checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the

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Description

providing a possible therapeutic target against neuroblastoma

This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck

The rat protein can also interact with alpha-actinin-4

This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition

CD6 Polyclonal Antibody, 100ul[BT-AP01767] Vacuum Filter providing a possible therapeutic targetIn response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. Checkpoint kinase 2 encoded by CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the

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