GPVI Polyclonal Antibody, 20ul Serological Pipets Mutation and knockout studies of
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GPVI Polyclonal Antibody, 20ul Serological Pipets Mutation and knockout studies ofThis gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet type bleeding disorder 11
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