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OMG Polyclonal Antibody, 50ul DNA Fragments as described in human patients

SKU: 92502975889

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OMG Polyclonal Antibody, 50ul DNA Fragments as described in human patientsOligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine rich repeat domain, a highly conserved region in OMG that influences cell proliferation, formation and maintenance of myelin

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Description

as described in human patients with lissencephaly

The gene was identified through a positional cloning approach

It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity

leading to the activation of MAPK and STAT signaling pathways

This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane

OMG Polyclonal Antibody, 50ul DNA Fragments as described in human patientsOligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine rich repeat domain, a highly conserved region in OMG that influences cell proliferation, formation and maintenance of myelin

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