HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix A nonconventional nuclear localization sequence

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

probably to asymmetric dimethylarginine

DLG-like (see DLG1

Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure

The protein encoded by NOP56 is similar in sequence to Nop56p and is also found in the nucleolus

HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix A nonconventional nuclear localization sequenceHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.