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FoxO3A Polyclonal Antibody, 100ul[BT-AP03334] Funnels Elastase subfamily

SKU: 8913565248

4.4
USD141.00 USD165.00

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FoxO3A Polyclonal Antibody, 100ul[BT-AP03334] Funnels Elastase subfamilyFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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Description

Elastase subfamily

Mutations in this gene are associated with mitochondrial complex I deficiency

Mutations in this gene have been associated with individuals affected by severe intellectual disability| early-onset epilepsy| microcephaly| congenital cataracts| growth retardation| and spasticity (PMID: 25439727)

Its excitation peak is 514nm and its emission peak is 527nm

Also catalyzes actin polymerization in the absence of Arp2/3

FoxO3A Polyclonal Antibody, 100ul[BT-AP03334] Funnels Elastase subfamilyFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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