Ksr-1(Phospho Ser392) Polyclonal Antibody, 50ul Proteases It is ubiquitously expressed in

It is ubiquitously expressed in normal tissues and in tumor cells

disease:Defects in NOTCH1 are a cause of aortic valve disease

have been described for this gene

Also binds iron-free LCN2 (apo-24p3)

This gene encodes a member of the SEC22 family of vesicle trafficking proteins

Ksr-1(Phospho Ser392) Polyclonal Antibody, 50ul Proteases It is ubiquitously expressed inThe sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Location regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity.,PTM: Phosphorylated on Ser 309 and, to a higher extent, on Ser 404 by MARK3. Dephosphorylated on Ser 404 by PPP2CA.