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S12A3 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis This gene encodes a nuclear

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S12A3 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis This gene encodes a nuclearThis gene encodes a renal thiazide sensitive sodium chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome a disease similar to Bartter's syndrome that is characterized by hypokalemic alkalosis combined with hypomagnesemia low urinary calcium and increased renin activity associated with normal

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Description

This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes

Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation

tissue specificity:Preferentially detected in breast carcinoma tissue and mammary gland

It associates with CDK5 to form an active kinase

An important paralog of OR8J3 is ENSG00000279961

S12A3 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis This gene encodes a nuclearThis gene encodes a renal thiazide sensitive sodium chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome a disease similar to Bartter's syndrome that is characterized by hypokalemic alkalosis combined with hypomagnesemia low urinary calcium and increased renin activity associated with normal

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