COL12A1 Polyclonal Antibody, 50ul RNA Synthesis Expansion of a polyalanine tract

Expansion of a polyalanine tract and other mutations in this gene cause X-linked mental retardation and epilepsy

The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate

induction:Down-regulated in many primary skin melanomas

The cadherin 20 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats

Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a protein that in humans is encoded by the RUNX1 gene

COL12A1 Polyclonal Antibody, 50ul RNA Synthesis Expansion of a polyalanine tractThis gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.