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NFKappaB-p100 Polyclonal Antibody, 100ul[BT-AP05973] Sealing Film Known functions for this protein

SKU: 7967399945

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NFKappaB-p100 Polyclonal Antibody, 100ul[BT-AP05973] Sealing Film Known functions for this proteinNFKB2 encodes a subunit of the transcription factor complex nuclear factor kappa B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. Nuclear factor kappa B subunit 2 encoded by NFKB2 can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full length protein is co translationally processed into a

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Description

Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases

and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism

The protein encoded by this gene resides in the ER| and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen

Although the encoded protein is a member of the peptidase S1 family of serine proteases

|online information:Interleukin-7 entry|Belongs to the IL-7/IL-9 family

NFKappaB-p100 Polyclonal Antibody, 100ul[BT-AP05973] Sealing Film Known functions for this proteinNFKB2 encodes a subunit of the transcription factor complex nuclear factor kappa B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. Nuclear factor kappa B subunit 2 encoded by NFKB2 can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full length protein is co translationally processed into a

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