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The majority of these follow-on patents were filed between 2021 and 2022, coinciding with the launches of Mounjaro and Zepbound (Figure 10)

The disease tends to be more active during the first few years after being diagnosed, and in people under the age of 40

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Symptoms usually develop about a week after infection and include frequent watery, or "explosive," diarrhea, loss of appetite, weight loss, stomach cramps, bloating, nausea, vomiting, fatigue and a low-grade fever.

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