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Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo

This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease

May have relatively low activity

Demethylation is performed by JMJD6

PNKD Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Conquer any lab challenge withThis gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.