PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Defects in TMEM237 are a

Defects in TMEM237 are a cause of Joubert syndrome-14

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins

Cells adhere strongly to the surface because of the advanced hydrophilic treatment

Yeast Mob1 binds Mps1p

and serve to maintain the integrity of the extracellular matrix

PHLD Polyclonal Antibody, 20ul Nucleic Acid Amplification Defects in TMEM237 are aMany proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma