phospho-MLKL (S358) mouse Monoclonal Antibody(6B4), 50ul Syringe Filter type II) encodes a protein

type II) encodes a protein that belongs to the serine/threonine protein kinase family of proteins

Mutations in this gene cause congenital heart defects| multiple types| 2 (CHTD2)

Alternatively spliced transcript variants encoding different isoforms have been found for ARAF

GO annotations related to this gene include enzyme binding and RNA polymerase II transcription corepressor activity

The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes

phospho-MLKL (S358) mouse Monoclonal Antibody(6B4), 50ul Syringe Filter type II) encodes a proteinThis gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase like domain however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF) induced necroptosis, a programmed cell death process, via interaction with receptor interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor