SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos This protein exhibits mitogenic activity

This protein exhibits mitogenic activity for keratinizing epidermal cells

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

Studies in other mammals suggest this protein plays a role in cell adhesion

OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS)

The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos This protein exhibits mitogenic activityThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding