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Keratin 37/38 Polyclonal Antibody, 20ul Human Genome Knockout Libraries It contains N-terminal transmembrane helices

SKU: 69858322905

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Keratin 37/38 Polyclonal Antibody, 20ul Human Genome Knockout Libraries It contains N-terminal transmembrane helicesThe protein encoded by KRT37 (keratin 37) is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.

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Description

It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity

The encoded protein is localized to the endoplasmic reticulum

and oligomerization domains

Schwann cells and fibroblasts

Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3)

Keratin 37/38 Polyclonal Antibody, 20ul Human Genome Knockout Libraries It contains N-terminal transmembrane helicesThe protein encoded by KRT37 (keratin 37) is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.

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