semaglutide aging Could Ozempic affect biological aging? New research suggests it might, but the story is still early. Scientists at the University of California, San Diego studied semaglutide, the active ingredient in GLP-1 medications Semaglutide and Skin: How Weight

Peptides May Be Preferred When: You want to preserve natural testosterone production and HPG axis function Fertility is a current or future concern Testosterone levels are mildly to moderately low (300-500 ng/dL) Symptoms are present but not severely impacting quality of life You prefer a therapy that works with your bodys natural systems You are interested in the additional benefits of GH optimization alongside testosterone support TRT May Be Preferred When: Testosterone levels are severely low (below 250 ng/dL) Symptoms are significantly impacting daily function and quality of life Primary hypogonadism (testicular failure) is the diagnosis, where the testes cannot respond to stimulation Faster and more predictable results from testosterone therapy are clinically important Previous peptide therapy has not produced adequate improvement In some cases, a combined approach using both peptides and TRT may be optimal

Proc Natl Acad Sci U S A 113(9):24302435

Wegovy is also approved to reduce excess weight and maintain weight reduction long term in certain adults with obesity or overweight and certain children with obesity, for use in addition to a reduced calorie diet and increased physical activity

However, the specific sites that are involved in mediating GLP-1R induced hypophagia are not completely understood

As research continues, it is becoming more and more apparent that their benefits extend beyond glucose regulation