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EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Four isoforms of CABC1 exist

SKU: 682000641

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EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Four isoforms of CABC1 existThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

Four isoforms of CABC1 exist due to alternative splicing events

Tyrosine phosphorylation seems to occur only at the plasma membrane

This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases

The adenosine A1 receptor encoded by ADORA1 is an adenosine receptor that belongs to the G-protein coupled receptor 1 family

Tyrosine-protein kinase SYK is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses

EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Four isoforms of CABC1 existThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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