TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis Defects in this gene lead

Defects in this gene lead to many pathophysiologic problems

and a widespread distribution in the brain

often at the N- or C-terminus of the protein

The protein includes an N-terminal SCAN domain| and seven C2H2-type zinc finger motifs

Another variant encoding an N-terminally truncated isoform has been reported

TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis Defects in this gene leadTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.