Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression suggesting that it may have

suggesting that it may have a role in transcription regulation

This gene encodes a member of the Rho family of small GTPases

and their phosphorylation is essential for the Catalytic activity of the N-terminal kinase domain

suggesting that this kinase may serve as an intermediate in the response to cellular stress

This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression suggesting that it may haveMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.