CD47 Polyclonal Antibody, 100ul Cell Senescence Alternative splicing of downstream exons

Alternative splicing of downstream exons is also observed| which results in different forms of the stimulatory G-protein alpha subunit| a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses

Interacts with HEXIM1 and MAP1S

Belongs to the V-ATPase e subunit family

Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG)

and maps to human chromosome 12p12

CD47 Polyclonal Antibody, 100ul Cell Senescence Alternative splicing of downstream exonsCD47 encodes a CD47 molecule, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript