CD55 Polyclonal Antibody, 100ul[BT-AP01880] Shakers 1987 [PubMed 2446322]

1987 [PubMed 2446322]

whereby it binds complement C8 and/or C9 during the assembly of this complex

Alternative splicing results in two transcript variants encoding distinct isoforms

The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg)| a macromolecular precursor in thyroid hormone synthesis| while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg

There are pseudogenes for this gene on chromosomes 22 and X

CD55 Polyclonal Antibody, 100ul[BT-AP01880] Shakers 1987 [PubMed 2446322]The first component of complement is a calcium dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+) dependent C1s C1r C1r C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full length C1r chain and the cleaved B chain.