STP1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which mediates the nucleocytoplasmic transfer

which mediates the nucleocytoplasmic transfer of proteins and RNAs

It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues

PGBD1 product is specifically expressed in the brain

The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene

Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6

STP1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which mediates the nucleocytoplasmic transferTransition protein 1 is a spermatid specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1 MIM 182880; PRM2 MIM 182890) (Luerssen et al. 1990