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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage The encoded protein is mainly

SKU: 61336067720

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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage The encoded protein is mainlyThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases

An important paralog of this gene is HSH2D

MOB4 was identified based on its similarity with the mouse counterpart

Several alternatively spliced transcripts have been described

Mutations in this gene can result in B cell deficiency and agammaglobulinemia

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage The encoded protein is mainlyThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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