Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research and comes sterile for convenience

and comes sterile for convenience

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase

This tyrosine phosphatase is a nuclear protein

The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5

Mutations in KRT10 are associated with epidermolytic hyperkeratosis

Nibrin Polyclonal Antibody, 100ul[BT-AP06020] Protein Research and comes sterile for convenienceMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.