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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment MIB1 (mindbomb E3 ubiquitin protein

SKU: 58301736285

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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment MIB1 (mindbomb E3 ubiquitin proteinSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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Description

MIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase

MARK proteins phosphorylate MAPs within their microtubule binding domains

This protein does not bind DNA directly

TACC3 encodes a member of the transforming acidic colied-coil protein family

Inward rectifier potassium channel 2

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment MIB1 (mindbomb E3 ubiquitin proteinSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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