UBS3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The activity of this ubiquitin

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis

localizes to a region of the Y chromosome frequently deleted in infertile males

|tissue specificity:Expressed in hematopoietic cells and also in colon and testis

and at slightly lower levels in fetal brain

This gene is clustered with WNT3

UBS3B Polyclonal Antibody, 50ul Adeno-associated Virus Packaging The activity of this ubiquitinThis gene encodes a protein that contains a ubiquitin associated domain at the N terminus, an SH3 domain, and a C terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet derived growth factor receptor.