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Dryness: Excessive use can cause dryness, flaking and tightness of the skin

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Changes relative to baseline lean mass were similar between the groups, and meta-regression analysis indicated that reductions in total body weight were significantly associated with fat mass loss but not with lean mass

You can also verify this using the units to milligrams conversion guide or the 20 units conversion reference

The oral tablet formulation, branded as Wegovy semaglutide tablets, was approved by the US Food and Drug Administration (FDA) in December 2025 following the Phase 3 OASIS 4 clinical trial