Rat Bactericidal Permeability-increasing Protein, BPI ELISA Kit, 96T Microplate Mixer where BRE is released as

where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein

and has glycosaminoglycan attachment sites in the acidic C-terminal region

The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance

Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies

CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs

Rat Bactericidal Permeability-increasing Protein, BPI ELISA Kit, 96T Microplate Mixer where BRE is released asThe cytotoxic action of BPI is limited to many species of Gram negative bacteria; this specificity may be explained by a strong affinity of the very basic N terminal half for the negatively charged lipopolysaccharides that are unique to the Gram negative bacterial outer envelope.