RPTOR Polyclonal Antibody, 50ul Cellular Function Assays This protein may function as

This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration

Two alternative transcript variants encoding different protein isoforms have been described for this gene

The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein

Mutations in this gene result in pontocerebellar hypoplasia type 2

Optic Atrophy

RPTOR Polyclonal Antibody, 50ul Cellular Function Assays This protein may function asThis gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E binding protein 1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript